You can get the formulation as either 2% or 5%. This means that topical Minoxidil is actually effective. However, in order to achieve optimal results, finasteride should be taken regularly and permanently, just like minoxidil. We can go back to topical minoxdil. During 6 months of follow-up, blood pressure did not change, whereas minoxidil increased heart rate by 3-5 beats min-1. Firstly, the results showed that of all the patients who used the combined topical solution, 90% "experienced moderate to marked improvement." In addition, the Topical Finasteride and Minoxidil solution was shown to be "significantly superior to Minoxidil alone" in improving hair density and hair diameter. Topical minoxidil has been used to treat frontal fibrosing alopecia (FFA), a scaring alopecia condition affecting the frontal and temporal hairlines.66 In a case review, 50% of FFA patients (n=7) cotreatment with 2% MS applied twice daily and systemic steroids or finasteride showed slow disease progression.67 Another type of scarring alopecia reported to be improved by topical minoxidil is traction alopecia. Topical minoxidil is a treatment for hair loss in males and females. Find everything you need to know about Rogaine (Minoxidil Topical), including what it is used for, warnings, reviews, side effects, and interactions. Side effects do not occur in the vast majority of cases. numbness or tingling of hands, feet, or face. Topical finasteride is typically compounded in gel or solution form. Mar 22, 2017. #8. itsjustsimon said: Around 25 drops are in 1ml. Tuesday, September 13, 2022. Of these, the strongest and most effective is the 5% men's solution. * low blood pressure. Realistic appraisal of the restorative and/or preventative potentials of topical minoxidil in androgenetic alopecia is needed. Minoxidil is available in the market in concentrations of 2% and 5% topical solutions. Conventional treatments include the use of topical minoxidil (MNX) formulations to stimulate hair growth and restore hair condition. Unlike minoxidil, finasteride is taken orally or as topical finasteride solution. If you're experiencing the rare side effects of oral Finasteride, then our topical Finasteride-Minoxidil spray could be for you. Minoxidil is a vasodilator that widens the blood vessels for efficient blood flow. 9,5 months, July, checked for prostatitis. Another group received a placebo topical foam until week 24 . Jul 9, 2019. Side effects of Oral Minoxidil. Child 12-17 years. We can even go back on a bit of topical minoxidil (three times weekly) with a bit of oral minoxidil (0.625 mg daily). (2) breathing difficulties. Minoxidil was initially used as a oral medication to reduce blood pressure. This drug is used topically to treat baldness. Minoxidil is the only licensed topical product for hair loss . Skin reactions are largely due to the presence of the propylene glycol vehicle in minoxidil solution. The characteristic feature of being non-scarring and reversible in the initial . Minoxidil 5% solution: Apply 1 milliliter (mL) twice daily to the center of the affected scalp. Please note that Minoxidil will not grow hair on a bald scalp. Scalp sulfotransferase changes minoxidil into minoxidil sulfate, the active form of the molecule. This is not a complete list of side effects and others may occur. 2018 update: A systemic review of topical finasteride shows consistent reduction in hair loss. Topical minoxidil can be an effective treatment choice for many manifestations of hair loss, thinning, and patchiness in both men and women. The study confirmed that a higher percentage formulation was more effective in increasing hair regrowth and "the magnitude of its effect was marked (45% more hair regrowth than 2% topical minoxidil at week 48)." Dosages of Minoxidil Topical: Dosage Forms and Strengths. Minoxidil side effects can include irritation where the medication has been applied; dizziness, light-headedness, and headaches; and chest pain. swelling of face, hands, feet, or lower legs. Rare or very rare With oral use. Effectiveness Results 6-12 months Monthly from 39 /month 3 months Not only does Oral Minoxidil rarely work as hoped, higher doses of oral Minoxidil all too often result in nasty side effects that simply aren't common for topical treatments. Materials and Methods: A retrospective assessment was done in 50 male patients aged 20-40 years with AGA. There is some exciting new evidence that suggests topical treatments may be viable alternatives for hair loss that present less risk of side effects. After 36 weeks, the men who were treated using 5% minoxidil showed a greater increase in hair regrowth around the hairline and crown than the men who were treated with the higher-strength 10% minoxidil solution. Treatment should be discontinued if there is persistent redness or irritation of the scalp. All the patients had been initially treated . * heart rhythm . Hair growth is usually observed after the medicine has been used for at least 3 to 6 months and lasts . Minoxidil is not effective in halting the receding hairline on the frontal scalp. Both concentrations are FDA approved for men and women. Frequency not known With oral use. The oral version can come in pill, capsule or tablet form. A study in Germany examined the long-term effects (104 weeks) of Minoxidil topical foam (MTF). Their review revealed that the effectiveness of topical minoxidil in treating hair loss has been largely demonstrated in men aged 18 to 41. It has been shown to have effectiveness in hair loss beyond androgenic alopecia as well, and off-label use of topical minoxidil is common in the treatment of hair loss, including: Alopecia areata In a study conducted on 52 female subjects with female pattern hair loss, it was determined that 1 mg of oral minoxidil was equally as effective as 5% topical minoxidil applied daily. There's 50mg of minoxidil in 1 ml, so that means 1 drop ~ 2.5mg of minoxidil. Child 1 month-11 years. Male: Apply 1 mL of 2% or 5% solution to affected areas of the scalp every 12 hours (every morning and evening); no more than 2 mL in 24 hours Minoxidil - What is it for. It thickens hair strands and prolongs the growing phase of the hair. If it is found effective, it . While the original trade name of minoxidil was Rogaine, later different versions of minoxidil have been available in the hair care industry. However, those treatments are associated with limited performance and a lack of tolerability and compliance due to the . 5% Topical Solution (Minoxidil Solution and Minoxidil Lotion): Recommended for men, newly formulated. This paper is a review and summary of the reported efficacy and safety of topical minoxidil in the treatment of androgenetic alopecia. Minoxidil topical solution should not be mixed with any hair oil. If you have any questions, contact a member of your healthcare team directly. The drug helps to inhibit the body's changing . Leucopenia; skin reactions; Stevens-Johnson syndrome; thrombocytopenia. Topical Spray (minoxidil) May 12, 2022 14:01; Updated; Minoxidil safety information . So you need to understand the possible side effects of minoxidil and especially, higher . Topical Minoxidil : Effectiveness & Limitations . At the end of the 12-weeks treatment period with 15 % minoxidil topical solution, 60 percent of women responded to the treatment and saw a significant increase in hair counts (>13.7 % on avg.). It won't help people who've already gone completely bald. 2%; 5%; Dosage Considerations - Should be Given as Follows: Androgenetic Alopecia. Ideally, the increase in hair density was predominant among the subjects using oral minoxidil. This is due to the inclusion of propylene glycol, which is a. Available topical formulations . In fact, a one-year study of minoxidil found that 84.3 percent of balding men who were treated using topical minoxidil rated the medication as either "very effective," "effective" or "moderately effective" for improving hair growth. The 5% minoxidil may be too strong for women and should be avoided. . Oral minoxidil has a much better response percentage than topical, but it is worth noting that this response and statistical improvement in hair doesn't necessarily equate to cosmetically significant improvement. Noticed face skin slump. The exact way that this medicine works is not known. topical gets it directly onto the scalp to improve blood flow. If you're a patient at MSK and you need to reach a provider after 5:00 p.m., during the weekend, or on a holiday, call 212-639-2000. We can go down to 0.625 mg alternating with 1.25 mg in hopes the hair growth stays okay. lightheadedness. * high heart rate. Compared . Minoxidil is applied to the scalp to promote hair growth and slows down the balding process. aim of the following study is to assess the efficacy of maintaining hair growth with 5% topical minoxidil fortified with 0.1% finasteride in patients with AGA after initial treatment with 5% topical minoxidil and oral finasteride for two years. The 5% solution is probably more effective but it may result in greater irritation than the 2% solution. The men's versions come in a 5% solution and a 5% foam while women's products are the 5% foam and 2% solution. Minoxidil topical solution should not be massaged into the scalp, but applied lightly. Systemic cardiovascular effects during chronic treatment with topical minoxidil vs placebo were evaluated using a double-blind, randomized design for two parallel groups (n = 20 for minoxidil, n = 15 for placebo). Since then FDA has approved its use for hair growth. 2% Topical Solution: Commonly known as Rogaine (first liquid formulation). It is no longer recommended for men but still in use by women to reverse hair loss. Well, this is tricky. Topical finasteride has been explored by many users to lower side effects of finasteride pill. Find 47 user ratings and reviews for Minoxidil Topical on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction The 5% minoxidil foam was shown to be effective in the treatment of male androgenetic alopecia in a 16 week trial. These side effects include: * dizziness. A clinical trial comparing the effectiveness of 5% and 2% minoxidil concluded that men using 5% concentrated minoxidil experienced 45% better than the 2% group. but, the side effects will also increase significantly. In this study, 26 women received oral minoxidil and 26 women received topical minoxidil. Minoxidil then works to increase the flow of blood to the affected areas of your scalp. However, minoxidil is less prone to sexual side effects. (6) pain in the chest, shoulders and arms. * weight gain from fluid retention. However, the difference was not statistically significant. Topical finasteride has been explored by many users to lower side effects of finasteride pill. Its mechanism of action is not well-established. (3) digestive problems. [7] Minoxidil is quite effective when started in early stages of hair loss and used regularly. For external use only. Positive. This blog will discuss (1) if the topical finasteride works, (2) whether it has fewer side effects, (3) the best way to avoid side effects, (4 . What minoxidil is used for. There are many options here. People take oral minoxidil in very low doses, like ~2mg. Continuous use of Minoxidil topical solution is needed to maintain hair regrowth. As a side effect hair growth was identified. In a 2014 study, researchers found that 5% minoxidil foam was effective at treating hair loss in women. This ensures your follicles have the nutrients they require to grow and thrive. weight gain (rapid) Other side effects not listed may also occur in some patients. Results showed that minoxidil is more effective than placebo in promoting total and nonvellus hair growth (mean difference [MD], 16.68; 95% confidence interval [CI], 9.34-24.03 and MD, 20.90; 95% CI, 9.07-32.74). Minoxidil is marketed in New Zealand as Rogaine Topical Solution (5%) and Headway Topical Solution (2% and 5%). 2020). I'm not a chemist but I think it does not really matter if it dilutes, you just need to put this sh*t down the throat. For example, a recent study published in the Journal of Dermatological Treatment compared the effectiveness of 5% and 10% topical minoxidil as treatments for male pattern baldness. The prescription drug finasteride is, along with surgical hair transplantation, one of the most effective alternatives to minoxidil. (4) hair growth in unwanted places. When a person uses this drug with finasteride, it can be up to 60% effective in preventing hair loss and encouraging new hair. Common side effects of minoxidil topical may include: changes in the color or texture of your hair. Side-effects, further information Abstract Background: Topical minoxidil solution 2% stimulates new hair growth and helps stop the loss of hair in individuals with androgenetic alopecia (AGA). One study, performed in 2002, compared the effects of 5 percent topical minoxidil versus 2 percent topical minoxidil in men with AGA . Finasteride is not approved for hair loss in women and is available by prescription for men only. Publication types . Topical Solution. Oral minoxidil is effective at as low as 0.25mg once daily and it has a half life of 4h (vs 22h for topical). Canceled Minoxidil after 9 months simply because of itchy skin. It takes several months (2-4) to regrow hair by twice-a-day application. Initially 5 mg daily in 1-2 divided doses, then increased in steps of 5-10 mg daily, increased at intervals . According to the research which has been carried out over the years, it has been revealed that Minoxidil and Finasteride are the most successful treatment for hair loss in the category of medications. Further studies are needed to assess its effects on middle-aged to late-aged men and women. if you are a non responder to topical thats just the luck of the draw. Adverse effects of topical minoxidil may include: Local redness, itching, and flaking. So I'm doing 5mg in the morning and 5mg in the evening. The drug should not be used more than two times a day, or be taken orally or applied . Finasteride pill (brand name Propecia) is one of the only two FDA approved products for hair loss treatment. After 24 weeks of treatment, there was . Minoxidil is poorly absorbed through the skin (less than 4%) [3], and plasma concentrations of minoxidil are far less than 10% of the mean minoxidil concentration present 2 hours after oral ingestion of 5 mg, the lowest dose for the treatment of hypertension [4].However, there have been reports of hypotension and tachycardia after chronic scalp application of minoxidil, suggesting that topical . Finasteride pill (brand name Propecia) is one of the only two FDA approved products for hair loss treatment. Did not help with ED. Skin over all the body seemed a bit loose. The results of anecdotal and controlled clinical trials are included. All topical forms are sold over-the-counter (OTC) and do not require a prescription. Thus, topical minoxidil would seem to be a useful treatment modality for patients with alopecia androgenetica a disease for which no other safe and effective drug therapy exists. The improvement rate varies from person to person. Melvin- Moderator Administrators 17.8k Author While the minoxidil 2% formulation is excellent for women, the minoxidil 5% solution has enough potency to stimulate men's hair growth. Rather, it's suitable for treating just hair loss. Oral Minoxidil can be combined with finasteride, which is a medication that can be taken specifically to combat male patterned baldness. Minoxidil topical side effects (more detail) With topical use. Rogaine is most effective for people who start using it at the first signs of hair loss. 84.3% of the patients rated the minoxidil solution as "very effective", "effective", or "moderately effective", while 15.7% of the patients rated it "ineffective." An 8-12 Month Study on 143 Male AGA Patients - including the placebo effect (2) In 2003, a Johnson & Johnson sponsored study was conducted on 143 patients with male pattern baldness.